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Main Title Opioid peptides : medicinal chemistry /
Other Authors
Author Title of a Work
Rapaka, Rao S.
Barnett, Gene.
Hawks, Richard L.
Publisher Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse, For sale by the Superintendent of Documents, U.S. Government Publishing Office
Year Published 1986
Stock Number 017-024-01297-1
OCLC Number 14266643
ISBN $11.00
Subjects Endorphins--Congresses ; Pharmaceutical chemistry--Congresses ; Chemistry, Clinical ; Enkephalins ; Peptides--analysis ; Opioids
Internet Access
Description Access URL
(paper) http://catalog.gpo.gov/fdlpdir/locate.jsp?ItemNumber=0831-C-08&SYS=000246892
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJEM  QP552.E53O644 1986 OCSPP Chemical Library/Washington,DC 06/14/2002
Collation viii, 376 pages : illustrations ; 23 cm.
Notes
"Based upon papers ... from the technical review on the medicinal chemistry and molecular pharmacology of opioid peptides and the opiates which took place on September 4-6, 1984, at Bethesda, Maryland"--Page iv. "Printed 1986"--Page 4 of cover. Shipping list no.: 1986-751-P. Includes bibliographical references.
Contents Notes
Frontiers of research in the medicinal chemistry and molecular pharmacology of opioid peptides / Rao S. Rapaka -- Synthesis of opioid peptide analogs / John M. Stewart -- Structure-activity relationships of opioid peptides / J.S. Morley and A.S. Dutta -- Design principles : enkephalins with predictable mu/delta receptor specificity / Yasuyuki Shimohigashi -- Structure-activity relationship and pharmacology of the highly selective u-opioid agonist, morphiceptin / Kwen-Jen Chang -- Dermorphin : autonomic pharmacology and structure-activity relationships / Giora Feuerstein -- Design of conformationally constrained cyclic peptides with high delta and mu opioid receptor specificities / Victor J. Hruby -- Dehydro and cyclopropyl amino acids and peptides / Charles H. Stammer -- Affinity labels as probes for opioid receptor types and subtypes / Phillip S. Portoghese and A.E. Takemori -- Peptide conformation and biological activity : a general review with examples of approaches relevant to opioid peptide function / Dan W. Urry -- Opioid peptides : analysis of specificity and multiple binding modes through computer-aided drug design and structure-activity studies / Raoul D. Nelson [and others] -- Mechanistic structure-activity studies of peptide and nonpeptide flexible opioids : an interdisciplinary approach / Gilda H. Loew [and others] -- Conformations of opioid peptides as determined by nuclear magnetic resonance and related spectroscopies / M. Abu Khaled -- Conformational analysis of opioid peptides and the use of conformational restriction in the design of selective analogs / Peter W. Schiller -- Stereochemically constrained enkephalin analogs containing x-aminoisobutyric acid and 1-amino- cyclopentane-1-carbolylic acid / Raghuvansh Kishore and Padmanabhan Balaram -- Enkephalin conformation in solution : a perspective from vibrational spectroscopic studies / V. Renugopalakrishnan [and others] -- Conformational features of the opioid peptides in the solid state : a review of x-ray crystallographic research / Arthur Camerman and Norman Camerman -- The search for nonaddicting strong analgesics : hopes and frustrations / Sydney Archer.