Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Pesticides epidemiological field studies /
Author Davies, John E.
Other Authors
Author Title of a Work
Durham, William F.
CORP Author National Environmental Research Center, Research Triangle Park, N.C. Pesticides and Toxic Substances Effects Lab.;Environmental Protection Agency, Washington, D.C.;Miami Univ., Fla. School of Medicine.
Publisher Office of Research and Development, U.S. Environmental Protection Agency ; Available from National Technical Information Service,
Year Published 1974
Report Number 68-02-1145; EPA-650/1-74-009; EPA-68-02-1145, EPA-R-802112
Stock Number PB-237347
OCLC Number 37660956
Subjects Pesticides--Toxicology.
Additional Subjects Pesticides ; Epidemiology ; Industrial medicine ; Urine ; Toxicology ; Blood serum ; Exposure ; Phosphorus organic compounds ; Carbamates ; Florida ; Phosphates ; Poisons ; Electroencephalography ; Recommendations ; Tables(Data) ; Parathion ; Phosdrin ; Air pollution effects(Humans) ; Metabolites ; Air sampling ; Urinalysis
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EIAD  EPA-650/1-74-009 Region 2 Library/New York,NY 03/31/2006 DISPERSAL
EJBD ARCHIVE EPA 650-1-74-009 Headquarters Library/Washington,DC 05/27/2014
EJBD  EPA 650-1-74-009 c.1 Headquarters Library/Washington,DC 05/27/2014
NTIS  PB-237 347 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation vi, 43 p. : ill. ; 28 cm.
The use of the multi-residue techniques for urinary metabolites provide the key to worker exposures from mixed organophosphate and carbamate exposures. Highly significant inverse correlations of cholinesterase levels with the dialkyl phosphate urinary metabolites were demonstrated under conditions of work exposure to the more toxic organophosphates such as ethyl-methyl parathion and Phosdrin. DEP, DETP, DMP and DMTP were the only alkyl phosphates regularly found in these occupational exposures. Following 8 hours of a work exposure to Dursban the appropriate dialkyl phosphate and phenolic derivatives persisted in the urine for 36 hours and longer. Severe and protracted illness was observed following intoxication by more polar and fat soluble organophosphates especially di-ethyl dichlorophenol phosphorothioate (VC-13). This pesticide and its metabolites were detected in serum and in urine 48 days after exposure. Additionally air sampling of the South Florida environment confirmed the disappearance of DDT and its metabolites.
Performed by University of Miami School of Medicine. Sponsored by Pesticides and Toxic Substances Effects Laboratory, National Environmental Research Center. Prepared for Office of Research and Development, U.S. Environmental Protection Agency. "June 1974." "EPA-650/1-74-009." EPA Project Officer: Dr. William F. Durham. Includes bibliographical references (p. 40).