||Initial Submission: Letter from Confidential Source to USEPA Reporting Results of 28-Day Dietary Toxicity Study in Purebred Beagle Dogs with (Confidential), A Substituted Aroyl Ester, Dated 12/09/1999. (Sanitized).
||; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
Laboratory animals ;
Toxic substances ;
Food consumption ;
Laboratory tests ;
Research and development ;
Test and methods ;
Substituted aroyl ester
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
The test substance was administered at 2500 and 5000 ppm in two animals/group (1/sex/dose). One male dog at 2500 ppm and both dogs at 5000 ppm exhibited unilateral corneal dystrophy. The abnormality appeared to be localized in the superficial layers of the cornea. There was no indication of corneal ulceration or irritation. This material is under research and development.