Includes bibliographical references and index.
Due to license restrictions, this resource is available to EPA employees and authorized contractors only

chapter 1. Redefining innovation / Jeffrey S. Handen -- chapter 2. Collaborations of the future / Melinda S. Shockley -- chapter 3. Portfolio management : selecting the right "set of projects" to meet product development goals / Arun Kejariwal -- chapter 4. Funding and resourcing clinical development / Michael A. Martorelli -- chapter 5. Emerging role of patients in clinical research / Michael S. Katz -- chapter 6. Innovative organizations : viewpoints of organizational scholars and practitioners / Lindsey Kotrba, Ia Ko, and Daniel R. Denison -- chapter 7. Moving toward personalized medicine : how to transform product development / Michele Pontinen, Jian Wang, and Christopher Bouton. "The biopharmaceutical industry has entered an era of unprecedented change and challenge, characterized by increasing pricing pressures, rising rates of attrition in the product development lifecycle, and decreasing scientific innovation. The most successful products are losing patent protection, and pipelines have been unable to fill the gap. This book explores the evolving definition of innovation in therapeutic product development and begins to examine its effects on and implications to the life sciences R&D industry vis-a-vis collaboration, communication, and integration"--Provided by publisher.