Main Title |
Human drug metabolism : from molecular biology to man / |
Other Authors |
|
Publisher |
CRC Press, |
Year Published |
1993 |
OCLC Number |
26098903 |
ISBN |
0849378109 (acid-free paper) |
Subjects |
Drugs--Metabolism ;
Drugs--Metabolic detoxification ;
Biotransformation ;
Pharmaceutical Preparations--metabolism ;
Sistema digestivo (farmacologia)--larpcal ;
Farmacologia geral e farmacocinetica--larpcal
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EJEM |
RM301.55.H86 1992 |
|
OCSPP Chemical Library/Washington,DC |
01/31/2003 |
|
Collation |
158 p. : ill. ; 27 cm. |
Notes |
Includes bibliographical references and index. |
Contents Notes |
Introduction / E.H. Jeffery -- Human cytochrome P450 enzymes and chemical carcinogenesis / F.P. Guengerich and T. Shimada -- cDNA-directed expression of human cytochrome P450 / F.J. Gonzalez and H.V. Gelboin -- Human P450 enzymes associated with the mephenytoin 4-hydroxylation polymorphism / J.L. Raucy and J.M. Lasker -- Assessment of drug oxidation in man in vivo / D.D. Breimer -- Covalent binding of acetaminophen estimated from protein adducts / H.E. Poulsen, D.W. Roberts and J.A. Hinson -- Xenobiotic metabolism studies with human liver / D.E. Chapman ... {et al.} -- Epoxide hydrolases: immunochemical detection in human tissues / T.M. Guenthner ... {et al.} -- Conjugation reactions in man: studies with diflunisal / R.K. Verbeeck -- Analysis of the specificity of human liver glucuronidation using cloned and stably expressed UDP-glucuronosyltransferases / B. Burchell ... {et al.} -- Properties of human cytosolic sulfotransferases involved in drug metabolism / C.N. Falany and J.A. Roth -- Acetylation pharmacogenetics / U.A. Meyer ... {et al.}. (cont) Glutathione S-transferase localization in human tumors / D.J. Harrison -- Glutathione conjugation in man / T.M.T. Mulders, D.D. Breimer and G.J. Mulder -- Alteration of drug biotransformation during the operation of host defense mechanism in humans / K.W. Renton. |