Record Display for the EPA National Library Catalog
RECORD NUMBER: 1 OF 14Main Title | Absorption and drug development : solubility, permeability, and charge state / | |||||||||||
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Author | Avdeef, Alex. | |||||||||||
Publisher | John Wiley & Sons, | |||||||||||
Year Published | 2012 | |||||||||||
OCLC Number | 759563379 | |||||||||||
ISBN | 9781118057452 (cloth); 1118057457 (cloth) | |||||||||||
Subjects | Drugs--Metabolism ; Adsorption ; Drug development ; Drugs--Design ; Pharmaceutical Preparations--metabolism ; Administration, Oral ; Cell Membrane Permeability ; Pharmaceutical Preparations--chemistry ; Structure-Activity Relationship | |||||||||||
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Edition | 2nd ed. | |||||||||||
Collation | xli, 698 p. : ill. ; 24 cm. | |||||||||||
Notes | Includes bibliographical references and index. |
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Contents Notes | Introduction -- Transport model -- pKa determination -- Octanol-water partitioning -- Liposome-water partitioning -- Solubility -- Permeability -- Pampa -- Permeability Caco 2/MDCK -- Permeability blood brain barrier. |