Climate change poses significant challenges to water resources and the Environmental Protection Agencys (EPA) National Water Program (NWP). The NWP 2012 Strategy: Response to Climate Change addresses climate change in the context of our water programs. It emphasizes assessing and managing risk and incorporating adaptation into core programs. Many of the programs and activities already underway throughout the NWP such as protecting healthy watersheds and wetlands; managing stormwater with green infrastructure; and improving the efficiency and sustainability of water infrastructure, including promoting energy and water efficiency, reducing pollutants, and protecting drinking water and public health are even more important to do in light of climate change. However, climate change poses such significant challenges to the nations water resources that more transformative approaches will be necessary. These include critical reflection on programmatic assumptions and development and implementation of plans to address climate changes challenges.