Record Display for the EPA National Library Catalog

RECORD NUMBER: 331 OF 886

Main Title Evaluation of the potential carcinogenicity of amitrole (61-82-5) /
CORP Author Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ;
Year Published 1988
Report Number EPA/600/8-91/060; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-004
Stock Number PB93-181659
Subjects Aromatic compounds--Carcinogenicity ; Amitrole--Carcinogenicity
Additional Subjects Carcinogens ; Toxicity ; Amitrole ; Humans ; Animals ; Dose-response relationships ; Carcinogenicity tests ; CAS 61-82-5
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB93-181659 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 20 pages ; 28 cm
Abstract
Amitrole is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'sufficient,' and the evidence from human studies is 'inadequate.' The potency factor (F) for amitrole is estimated to be 3.30/(mg/kg/day), placing it in potency group 2 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, amitrole is assigned a 'MEDIUM' hazard ranking for the purposes of RQ adjustment.
Notes
Cover title. "June 1988." Includes bibliographical references. Microfiche.