| Main Title |
Initial Submission: Draft Pathology Report (Terminal Kill) in 13-Week Inhalation Toxicity Study in the Rat with 13-Week Treatment-Free Period, with Cover Letter dated 12/07/1999. (Sanitized). |
| CORP Author |
UOP, Inc., Des Plaines, IL.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1999 |
| Report Number |
8EHQ-1299-14613S |
| Stock Number |
OTS0559860 |
| Additional Subjects |
Pathology ;
Inhalation ;
Toxicity ;
Rats ;
Lungs ;
Lymph nodes ;
Dosage ;
Laboratory animals ;
Histopathology ;
Respiratory system ;
Treatment ;
Responses(Biology) ;
Morbidity ;
Mortality ;
Terminal kill
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0559860 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
148p |
| Abstract |
There were treatment-related changes in the lungs and bronchial lymph nodes of all treated group terminal kill animals. Microscopically, the findings in the lung were characterised by mild to moderate histiocytosis/proteinosis associated with perivascular cuffing/pneumonitis and increased peribronchial lymphoid response. Lymphoid hyperplasia and minor histiocyte foci were also found in the bronchial lymph nodes. A no observable effect level (NOEL) was not established. |
