Record Display for the EPA National Library CatalogRECORD NUMBER: 7 OF 20
|Main Title||Evaluation of the potential carcinogenicity of 2,6-dinitrotoluene (123-91-1) /|
|CORP Author||Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.|
|Publisher||U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ;|
|Report Number||EPA/600/8-91/125; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-100|
|Additional Subjects||Dioxanes ; Toxicity ; Risk assessment ; Exposure ; Public health ; Hazardous materials ; Neoplasms ; Tolerances(Physiology) ; Carcinogenicity ; Dose-response relationships ; CAS Registry No: 123-91-1|
|Collation||25 pages ; 28 cm|
1,4-Dioxane is a probalble human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'Sufficient', and the evidence from human studies is 'Inadequate'. The potency factor (F) for 1,4-dioxane is estimated to be 0.34 (mg/kg/day)(-1), placing it in potency group 3 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, 1,4-dioxane is assigned a 'LOW' hazard ranking.
Cover title. "June 1988." Includes bibliographical references. Microfiche.