Record Display for the EPA National Library Catalog


Main Title Carcinogenicity assessment of aldrin and dieldrin.
Author Cavender, F. L. ; Cook, B. T. ; Page, N. P. ; Cogliano, V. J. ; Hajjar, N.
CORP Author United States. Environmental Protection Agency. Office of Health and Environmental Assessment.
Publisher Carcinogen Assessment Group, Office of Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency,
Year Published 1987
Report Number EPA/600/6-87/006
Stock Number PB88-139951
OCLC Number 17196864
Subjects Dieldrin--Carcinogenicity. ; Dieldrin--Toxicology. ; Insecticides--Toxicology. ; Pesticides--Toxicology.
Additional Subjects Carcinogens ; Carcinogenicity testing ; Pesticides ; Insecticides ; Toxicology ; Epidemiology ; Exposure ; Bioassay ; Laboratory animals ; Carcinogenesis ; Aldrin ; Dieldrin
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHAM  EPA/600/6-87/006 Region 1 Library/Boston,MA 05/25/2016
EJBD ARCHIVE EPA 600-6-87-006 Headquarters Library/Washington,DC 01/06/2014
EJED  EPA 600/6-87-006 OCSPP Chemical Library/Washington,DC 01/01/1988
EKBD  EPA-600/6-87-006 Research Triangle Park Library/RTP, NC 01/01/1988
EKCD  EPA/600/6-87/006 CEMM/GEMMD Library/Gulf Breeze,FL 07/25/2018
ERAD  EPA 600/6-87-006 Region 9 Library/San Francisco,CA 02/18/1994
ESAD  EPA 600-6-87-006 Region 10 Library/Seattle,WA 01/02/1998
NTIS  PB88-139951 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 1 volume (various pagings) : illustrations ; 28 cm
Evidence pertaining to the carcinogenicity of aldrin/dieldrin is reviewed and evaluated. The report covers studies completed before 1985. Case reports and epidemiologic studies of pesticide applicators and pesticide manufacturing workers are reviewed, but because of methodologic limitations, these studies established neither a positive nor a negative association between cancer and aldrin/dieldrin exposure. A number of independent studies of laboratory animals, however, demonstrated that aldrin/dieldrin cause liver cancer in mice and rats. Based on the accumulated evidence, aldrin/dieldrin are classified as probable human carcinogens, Group B2, using EPA's Guidelines for Carcinogen Risk Assessment. The carcinogenic potency of aldrin/dieldrin is estimated by fitting mathematical models to the laboratory animal data. These estimates indicate that aldrin/dieldrin are rather potent carcinogens, ranking in the second quartile of potential carcinogens evaluated by EPA's Carcinogen Assessment Group.
"Drafted by Dynamac Corporation, Rockville, Maryland, under EPA contract number 68-02-4131"--Page xiii. Distributed to depository libraries in microfiche. "August 1987." Includes bibliographical references (pages 6-1-6-10). "EPA/600/6-87/006."