Record Display for the EPA National Library CatalogRECORD NUMBER: 1 OF 2
|Main Title||Evaluation of the potential carcinogenicity of dibenz(a, h)anthracene (53-70-3) /|
|CORP Author||Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.|
|Publisher||U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ;|
|Report Number||EPA/600/8-91/104; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-078|
|Subjects||Aromatic compounds--Carcinogenicity ; Dibenz(a, h)anthracene--Carcinogenicity|
|Additional Subjects||Carcinogens ; Toxicity ; Risk assessment ; Carcinogenicity tests ; Humans ; Animals ; Dose-response relationships ; Dibenzanthracenes ; CAS 53-70-3|
|Collation||30 pages ; 28 cm|
Dibenz(a,h)anthracene is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). Evidence on potential carcinogenicity from animal studies is Sufficient, and the evidence from human studies is No Data. The bioassay used to calculate the potency factor suggests that dibenz(a,h)anthracene may be highly carcinogenic (i.e., all treated animals developed tumors, and therefore, there is no basis for calculating a specific human potency factor). Hence, dibenz(a,h)anthracene is assigned to potency group 1 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Combining the weight-of-evidence group and the potency group, dibenz(a,h)anthracene is assigned a HIGH hazard ranking for the purposes of RQ adjustment.
Cover title. "June 1988." Includes bibliographical references. Microfiche.