Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Initial Submission: Basic Toxicity of Acetoacet-O-Anisidide with Cover Letter dated 09/28/1992.
CORP Author Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1992
Report Number 8EHQ-0992-10946
Stock Number OTS0570984
Additional Subjects Toxicology ; Health effects ; Toxic substances ; Acetoacet-o-anisidide ; Acute toxicity ; Mammals ; Rats ; Oral ; Gavage ; Primary dermal irritation ; Guinea pigs ; Dermal ; Subchronic toxicity ; Primary dermal sensitization ; Primary eye irritation ; Rabbits ; Diet ; CAS No 92-15-9
Library Call Number Additional Info Location Last
NTIS  OTS0570984 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 05/27/2010
Collation 9p
Groups of five rats were fed 0.1 or 1.0% of the test compound in the diet for fourteen days. Abnormalities observed at the high-dose level included: decreased body weight gain, red blood cell count, hemoglobin concentration and hematocrit; changes in red blood cell morphology; and increased serum aspartate aminotransferase, urea nitrogen, and glucose. Gross and histopathologic abnormalities included darkening of the spleen and splenic congestion. A slight decrease in seruit glucose and splenic congestion were observed at the low-dose level. The test material has been used and sold as a pure chemical.