Record Display for the EPA National Library Catalog

RECORD NUMBER: 217 OF 308

Main Title Report on Toxicity Experiments in Guinea Pigs, Rabbits and Dogs (Sanitized).
CORP Author Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number 86-890001208S
Stock Number OTS0520720
Additional Subjects Toxicology ; Health effects ; Diphenyl Ether (101-84-8) ; Acute Toxicity ; Mammals ; Guinea Pigs ; Dermal ; Primary Dermal Irritation ; Rabbits ; Subchronic Toxicity ; Dogs ; Oral ; Toxic substances ; Laboratory animals ; CAS No 101-84-8
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NTIS  OTS0520720 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 13p
Abstract
Summary reports on toxicity tests of diphenyl ether indicate that it is not toxic to guinea pigs when applied as a saturated water solution, a 5% or 10% ethyl alcohol solution, or as 10% solution in Stoddard's solvent. Concentrations of 1, 5, and 10% in Stoddard's solvent applied daily for 1 week produced necrosis, while other solutions were non-irritating. Oral administration of 2.11 g/kg bw fed daily for 1 week produced no toxic effects in a dog.