Record Display for the EPA National Library Catalog

RECORD NUMBER: 147 OF 308

Main Title Initial Submission: Toxicological Investigation of Methyacrylonitrile with Cover Letter dated 07/23/1992.
CORP Author Younger Laboratories, St. Louis, MO.; Monsanto Chemical Co., St. Louis, MO.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1992
Report Number 8EHQ-0892-9600
Stock Number OTS0570516
Additional Subjects Toxicology ; Health effects ; Toxic substances ; Methacrylonitrile ; Acute toxicity ; Mammals ; Rats ; Oral ; Gavage ; Rabbits ; Dermal ; Primary dermal irritation ; Primary eye irritation ; Inhalation ; CAS No 126-98-7
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Status
NTIS  OTS0570516 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 12p
Abstract
The undiluted compound was fed by stomach tube to Syrague-Dawley strain albino male and female rats. After the approximate Minimum Lethal Dose was determined, groups of male and female rats were fed in increasing doses at increments of 0.2 fractional log intervals at four levels designed to blanket the toxicity range thereby supplying data for calculation of the LD50 which was done according to a modification of the method of E. J. de Beer. Observations were made for toxic symptoms and the viscera of the test animale were examined macroscopically.