Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Battery of Acute Toxicity Tests with Cover Letter.
CORP Author Food and Drug Research Labs., Inc., Conshohocken, PA. ;Rohm and Haas Co., Philadelphia, PA. Research Labs.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 23 Feb 1983
Year Published 1983
Report Number 878213508;
Stock Number OTS-0205842
Additional Subjects Toxicity ; Testing ; Dermal absorption ; Oral dosage ; Skin(Anatomy) ; Eye irritation ; Mortality ; Inhalation ; Respiratory distress ; Rats ; Rabbits ; Laboratory animals ; Exposure ; 4-(1,1,3,3-tetramethyl butyl)
Library Call Number Additional Info Location Last
NTIS  OTS-0205842 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 07/09/2008
Collation 40p
Six New Zealand albino rabbits, 2 to 3 kg, were closely clipped over the back and sides with an Oster electric clipper. A 0.5 gram portion of the test material was introduced under a 1.5 inch, 12-ply gauze patch placed directly over the test site and held in place with Dermicel tape. The rabbits were wrapped with rubber damming for an exposure period of 4 hours. Slight erythema was observed in 4 animals after 4 hours. All signs of irritation had disappeared in 24 hours. Rohm and Haas Company sample '6-8815, Octylphenol,' when applied to the skin of New Zealand albino rabbits in the quantity of 0.5 ml produced no signs of corrosivity.