| Main Title |
Evaluation of the Dermal Carcinogenic Potential of Pentaerythritol Acrylate-HF with Attachments and Cover Letter dated 07/28/88. |
| CORP Author |
Union Carbide Corp., Danbury, CT. ;Carnegie-Mellon Inst. of Research, Pittsburgh, PA.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
2 Aug 1988 |
| Year Published |
1988 |
| Report Number |
FYI-OTS-0888-0629; |
| Stock Number |
OTS-0000629 |
| Additional Subjects |
Carcinogens ;
Dermal absorption ;
Toxicity ;
Chemical hygine ;
Malignant neoplasms ;
Tumors ;
Pentaerythritol aerylate-HF ;
Union Carbide Corporation(Trademark) ;
511-01-6656 ;
16-CHC-111-3
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0000629 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
18p |
| Abstract |
Forty C3H/HeJ male mice were painted 3 times per week for their lifespan on the skin of the back, clipped free of fur, with pentaerythritol acrylate-HF as a 15% dilution in acetone at an average dose of 0.0026 grass pentaerythritol acrylate-HF/mouse/application. A negative control group of 40 C3H/HeJ male mice received repeated skin paintings of undiluted acetone at an average dose of 0.012 grams/mouse/application. No skin tumors were observed in the group of mice painted with pentaerythritol acrylate-HF. One mouse in the group painted with acetone had a histologically verified squamous cell carcinoma of the skin near the right eye which may or may not have been due to treatment. |
