chapter 1 Introduction to Toxicology: The Necessity of Measurement -- chapter 2 Normality: Definition and Maintenance -- chapter 3 Determination of Toxicity: The Basic Principles -- chapter 4 Determination of Toxicity: In Vitro and Alternatives -- chapter 5 Toxicology In Silico -- chapter 6 Safety Pharmacology -- chapter 7 Determination: General and Reproductive Toxicology -- chapter 8 Determination: Genotoxicity and Carcinogenicity -- chapter 9 Determination: Dermal Toxicity—Sensitization, Irritation, and Corrosion -- chapter 10 Determination: Environmental Toxicology and Ecotoxicology -- chapter 11 Interpretation: Basic Principles -- chapter 12 Interpretation: Different Data Types -- chapter 13 Prediction of Hazard -- chapter 14 Background to Risk due to Toxicity -- chapter 15 Risk Assessment in Practice and Setting Exposure Limits -- chapter 16 Safety Assessment of Extractables, Leachables, and Impurities -- chapter 17 Risk Assessment and Management in the Workplace -- chapter 18 Risk Assessment: Carcinogenicity, the Environment, Evolution, and Overview of Risk Assessment -- chapter 19 Evaluation of Specific Classes of Chemical -- chapter 20 Errors in Toxicology -- chapter 21 The Future of Toxicity Testing and Risk Assessment. Practical Toxicology: Evaluation, Prediction, and Risk, Third Edition shows how to conduct a program of safety evaluation and testing and then to interpret and apply the resulting data and information in the real world, beginning with the basic concepts in toxicology and progressing to the interpretation of the resulting data. Revised and updated chapters on risk assessment guide the reader to setting the foundations necessary for submission to regulatory authorities. In addition, a new chapter in the book reviews the errors in toxicology, mistakes, misuse, mismanagement, and misunderstanding with a view to avoiding these in the future.