Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Identification of aneuploidy-inducing agents using the wheat seedling assay /
Author Sandhu, S. S. ; Dhesi, J. S. ; Gill, B. S.
CORP Author Environmental Health Research and Testing, Inc., Research Triangle Park, NC. ;North Carolina Central Univ., Durham.;Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory,
Year Published 1989
Report Number EPA/600/D-89/091; EPA-68-02-4456
Stock Number PB89-223978
Additional Subjects Toxicity ; Mutagens ; Wheat plants ; Cyclophosphamide ; Chromium inorganic compounds ; Aneuploidy ; Mutagenicity tests ; Chromosome aberrations ; Alleles ; DNA repair
Library Call Number Additional Info Location Last
NTIS  PB89-223978 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation 17 pages ; 28 cm
A short-term assay using Chinese spring wheat for detecting induced aneuploidy and/or clastogenicity is described. The seed of virescent wheat (v1v1) are treated with a test agent. The appearance of white sectors (v1v1v1) or green sectors (v10) on the virescent leaves indicates the gain or loss of a chromosome or a segment of a chromosome bearing v1 allele. Three test chemicals, chromium trioxide (100-5,000 microg/ml), chromium dichromate (500-5,000 microg/ml), and cyclophosphamide (100-1,000 microg/ml) produced a dose-related positive response for chromosome aberrations in the assay.
EPA/600/D-89/091. PB89-223978. Microfiche.