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Main Title Use of Whole Embryo Culture for Evaluating Toxicity and Teratogenicity.
Author Sadler, T. W. ; Warner, C. W. ;
CORP Author North Carolina Univ. at Chapel Hill. School of Medicine.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1984
Report Number EPA-R-808888; EPA/600/J-84/104;
Stock Number PB85-104925
Additional Subjects Toxicity ; Embryo ; Culture(Biology) ; In vitro analysis ; Environmental surveys ; Feasibility ; Exposure ; Metabolism ; Economic analysis ; Rats ; Laboratory animals ; Reprints ; Teratogenicity
Holdings
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Status
NTIS  PB85-104925 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 8p
Abstract
The use of rodent embryos cultured in vitro for the evaluation of the teratogenicity of compounds is discussed in detail. Time and concentration of exposure are delineated as factors of importance, as well as metabolism and embryonic stage. The economic feasibility of using such systems is estimated.