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Main Title Ventilatory Patterns of Bluegill ('Lepomis macrochirus') Exposed to Organic Chemicals with Different Mechanisms of Toxic Action (Revised).
Author Carlson, R. W. ;
CORP Author Environmental Research Lab.-Duluth, MN.
Publisher c1990
Year Published 1990
Report Number EPA/600/J-90/255;
Stock Number PB91-144915
Additional Subjects Water pollution effects(Animals) ; Chemical water pollutants ; Freshwater fishes ; Respiration ; Structure-activity relationship ; Mucus membranes ; Cholinesterase inhibitors ; Electron transport ; Cough ; Reprints ; Lepomis macrochirus
Library Call Number Additional Info Location Last
NTIS  PB91-144915 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 18p
Bluegill (Lepomis macrochirus) were exposed to 13 organic chemicals representing five known toxic mechanisms and their ventilatory patterns examined for differential responses related to mechanism. Two quantifiable characteristics of the ventilatory pattern, ventilatory frequency and cough frequency, had diagnostic utility as clinical signs to differentiate chemicals that killed through narcosis from those that killed by other toxic mechanisms. Bluegill were also exposed to 2-chloroethanol and 2,4-pentanedione, chemicals previously considered as narcotic poisons but tested here as unknowns. Ventilatory patterns induced by these chemicals and time to death in LC100 concentrations support current theories that they kill by mechanisms other than narcosis.