Record Display for the EPA National Library Catalog
RECORD NUMBER: 2 OF 2
|OLS Field Name||OLS Field Data|
|Main Title||Two-Week Inhalation Toxicity Study with Emery 6724 in Rats with Cover Letter dated 01/19/90.|
|CORP Author||Du Pont de Nemours (E.I.) and Co., Newark, DE. Haskell Lab. for Toxicology and Industrial Medicine.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.|
|Publisher||23 Jan 1990|
|Additional Subjects||Rats ; Control groups ; Chemical analysis ; Inhalation toxicity study ; Emery 6724 ; Crl:CD4 4BR rats ; Liquid aerosol ; Blood samples ; Pathological exams|
Three groups of 10 male Crl:CD4(trademark)4BR rats were exposed 6 hours/day, 5 days/week for 2 weeks to a liquid aerosol of Emery 6724 at concentrations of 32, 110 or 290 mg/m (sup 3). Test atmospheres were generated by atomization of the test material in a high-pressure air stream and analyzed by gravimetric analysis. A procedural control group of 10 male Crl:CD4(trademark)4BR rats was exposed to air only. At the end of the exposure period, blood and urine samples were collected for clinical chemical analyses, and 5 rats per group were killed for pathologic examination. The remaining rats were retained for a 14-day post-exposure recovery period and then given the same clinical chemical and pathologic examinations.