The U.S. Environmental Protection Agency is today issuing five guidelines for assessing the health risks of environmental pollutants. These are: Guidelines for Carcinogen Risk Assessment; Guidelines for Estimating Exposures; Guidelines for Mutagenicity Risk Assessment; Guidelines for the Health Assessment of Suspect Developmental Toxicants; and Guidelines for the Health Risk Assessment of Chemical Mixtures. This notice contains the Guidelines for the Health Risk Assessment of Chemical Mixtures; the other guidelines appear elsewhere in todays Federal Register. The Guidelines for the Health Risk Assessment of Chemical Mixtures (hereafter Guidelines) are intended to guide Agency analysis of information relating to health effects data on chemical mixtures in line with the policies and procedures established in the statutes administered by the EPA. These Guidelines were developed as part of an interoffice guidelines development program under the auspices of the Office of Health and Environmental Assessment (OHEA) in the Agencys Office of Research and Development. They reflect Agency consideration of public and Science Advisory Board (SAB) comments on the Proposed Guidelines for the Health Risk Assessment of Chemical Mixtures published January 9, 1985 (50 FR 1170). This publication completes the first round of risk assessment guidelines development. These Guidelines will be revised, and new guidelines will be developed, as appropriate.

"EPA 630-R-98-002." "September 1986." "Risk Assessment Forum"--Cover. "Published on September 24, 1986, Federal Register 51(185):34014-34025." Includes bibliographical references (pages 19-22).