Record Display for the EPA National Library Catalog


Main Title Report of the EPA Workshop on the development of risk assessment methodologies for tumor promoters /
Author Connery, Jan. ; Spitzer, Hugh L.
Other Authors
Author Title of a Work
Connery, Jan.
CORP Author United States. Environmental Protection Agency. Office of Health and Environmental Assessment.
Publisher Office of Health and Environmental Assessment and Office of Regulatory Support and Scientific Analysis, Office of Research and Development, U.S. Environmental Protection Agency,
Year Published 1987
Report Number EPA/600/9-87/013
Stock Number PB88-230743
OCLC Number 17625877
Subjects Cocarcinogens--Research--Congresses ; Tumors--Genetic aspects--Research--Congresses ; Genetic engineering--Risk assessment--Congresses
Additional Subjects Risk assessment ; Tumors ; Methodology ; Tumor promoters ; Risk assessment ; Carcinogenesis
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHBD  EPA/600/9-87/013 CEMM/ACESD Library/Narragansett,RI 03/30/2007
EJED  EPA/600/9-87/013 OCSPP Chemical Library/Washington,DC 01/11/2002
EKBD  EPA-600/9-87-013 Research Triangle Park Library/RTP, NC 01/01/1988
ELBD ARCHIVE EPA 600/9-87/013 Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023 DISPERSAL
EMBD  EPA/600/9-87/013 NRMRL/GWERD Library/Ada,OK 08/25/2000
ESAD  EPA 600-9-87-013 Region 10 Library/Seattle,WA 03/23/2010
NTIS  PB88-230743 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 1 v. (various pagings) : ill. ; 28 cm.
At a workshop sponsored by the EPA Office of Research and Development, thirteen expert panelists discussed research needed to support the development of risk assessment methodologies for tumor promoters. The panelists exchanged current data on promotion, identified data gaps, and formulated general and specific research recommendations. Available data suggest that there are probably at least three stages of carcinogenesis - initiation, promotion and progression - and that there are agents that are associated predominantly with these three stages. The panelists agreed that the mechanism of promotion is not currently understood and they suggest that there may be several different mechanisms of promotion. Available data suggest that promotion is substantially different from initiation, and that traditional risk assessment models for carcinogens are not appropriate for promoters. The panelists agreed that not enough data are currently available to assess the risks of promoters, and that substantial research is needed in several areas.
Distributed to depository libraries in microfiche. "June 1987." Includes bibliographical references (p. 60-66). "EPA/600/9-87/013."