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Main Title Acute Eye Irritation Study in Rabbies C-47, C-48, and C-49. Final Report with Cover Letter.
CORP Author Hazleton Labs., Inc., Vienna, VA. ;Celanese Corp., Louisville, KY.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 19 Nov 1982
Year Published 1982
Report Number 878210265;
Stock Number OTS-0205925
Additional Subjects Eye ; Irritation ; Rabbits ; Glycidyl ether ; Toxicity ; Evaluation ; Hazardous materials ; Chemical compounds ; Dosage ; Testing ; Triglycidyl ether ; Trimethylol propane ; Cilanese Corporation
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  OTS-0205925 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 54p
Abstract
C-47, C-48 and C-49 were evaluated for eye irritation potential in rabbits. C-48 produced conjunctival redness in one unwashed and one washed eye at twenty-four hours. C-49 produced corneal opacity in four unwashed eyes; conjunctival redness in one washed and four unwashed eyes; chemosis in two unwashed eyes; and discharge in one washed and two unwashed eyes. C-47 produced no evidence of eye irritation. The purpose of this study was to evaluate the eye irritation potential of C-47, C-48 and C-49 in rabbits to the Federal Hazardous Substance Act, 16 CFR, and Part 1500.42. The study was initiated on December 26, 1978, and was terminated on January 2, 1979.