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RECORD NUMBER: 10 OF 18

Main Title Regression Methods for Data with Incomplete Covariates.
Author Whittemore, A. S. ; Grosser., S. ;
CORP Author Stanford Univ., CA. Dept. of Family, Community and Preventive Medicine.;Health Effects Research Lab., Research Triangle Park, NC.;National Institutes of Health, Bethesda, MD.;National Science Foundation, Washington, DC.;Alfred P. Sloan Foundation, New York.
Publisher c1986
Year Published 1986
Report Number EPA-R-813495-01 ;NIH-CA-23214; EPA/600/J-86/530;
Stock Number PB90-232158
Additional Subjects Epidemiology ; Regression analysis ; Statistical analysis ; Covariance ; Algorithms ; Reprints ; Chronic disease ; Maximum likelihood estimates
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NTIS  PB90-232158 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 18p
Abstract
Modern statistical methods in chronic disease epidemiology allow simultaneous regression of disease status on several covariates. These methods permit examination of the effects of one covariate while controlling for those of others that may be causally related to the disease. However, they do not accommodate data in which one or more covariates are incomplete, e.g. missing or measured with error. The paper uses assumptions about the probability laws governing covariate incompleteness to obtain estimates of regression coefficients relating disease to the unobserved complete covariates. The estimates are obtained by maximizing the likelihood of the observed incomplete data via the EM algorithm.