Record Display for the EPA National Library Catalog

RECORD NUMBER: 7 OF 65

Main Title D4 (octamethylcyclotetrasiloxane): in Vitro Chromosomal Aberrations Assay in Chinese Hamster Ovary Cells.
CORP Author Union Carbide Corp., Cleveland, OH.; Mellon Inst.-Union Carbide Corp., Export, PA. Bushy Run Research Center.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1994
Report Number 8EHQ-86940001609
Stock Number OTS0572644
Additional Subjects Toxicology ; Health effects ; Octamethylcyclotetrasiloxane ; Toxicity ; Genotoxicity ; Chromosomal effects ; Mammals ; Hamsters ; In Vitro ; CAS No 556-67-2 ; Octamethy1cyclotetrasiloxane ; Toxic substances ; Laboratory animals
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NTIS  OTS0572644 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 33p
Abstract
Treatment of cultured cho cells with D4 did not result in statistically significant or dose-related increases in the frequencies of chromosomal aberrations either in the presence or in the absence of a rat liver S9 metabolic activation system. Therefore, D4 was not considered to be clastogenic under the conditions of this in vitro test.