| Main Title |
Enhancement of Viral Transformation of Hamster Embryo Cells by Pretreatment with 4-Chloromethylbiphenyl. |
| Author |
Hatch, G. G. ;
Mamay, P. D. ;
Nesnow, S. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1981 |
| Report Number |
EPA-600/J-81-255; |
| Stock Number |
PB83-189605 |
| Additional Subjects |
Toxicology ;
Viruses ;
Cells(Biology) ;
Bioassay ;
Hamsters ;
Reprints ;
Biphenyl/chloromethyl ;
Carcinogenesis
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB83-189605 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
7p |
| Abstract |
Treatment of Syrian hamster embryo cells with 4-chloromethylbiphenyl produced reproducible and quantitative concentration-dependent enhancement of viral transformation the statistical significance of which was independent of cell lethality. These results suggest this compound has carcinogenic potential since positive results in this mammalian cell bioassay system closely correlate with the carcinogenic potential of many diverse compounds and with structurally similar agents, especially other chlorinated compounds. |
