Record Display for the EPA National Library CatalogRECORD NUMBER: 10 OF 16
|Main Title||Support document, health effects test rule : chlorinated benzenes.|
|Publisher||U.S. Environmental Protection Agency, Office of Pesticides and Toxic Substances,|
|Subjects||Chlorobenzene ; Environmental health--United States ; Chlorobenzenes--toxicity|
|Additional Subjects||Chlorobenzene ; Environmental health--United States ; Toxicology ; Chlorobenzenes ; Exposure ; Chlorohydrocarbons ; Chlorine organic compounds ; Physiological effects ; Assessments ; Laboratory animals ; Nervous system ; Signs and symptoms ; Testing ; Exposure ; Toxic substances ; Toxic Substances Control Act ; Public Law 94-469|
|Collation||163 pages : illustrations.|
Since chlorobenzenes are used as chemical intermediates and for other industrial purposes as well as in consumer products, there is very broad potential exposure. Thus, there is known or potential exposure of workers involved in chlorobenzene production, processing, and use, and of the general population, both directly from consumer products and indirectly through the environment. For this reason and on the basis of limited toxic effects studies, EPA has proposed that certain chlorobenzenes be tested to assess their potential to cause chronic, reproductive, teratological, and oncogenic effects. Following resolution of methodology issues the Agency has raised, EPA will propose at a later date test rules for neurotoxic and mutagenic effects. Further, the Agency has decided not to propose test rules for acute toxicity and epidemiological studies.
On cover: Assessment of testing needs : chlorinated benzenes : support document for proposed health effects test rule, Toxic Substances Control Act, Section 4. EPA-560/11-80-014. "June 1980." Includes bibliographical references (pages 142-163).