||Evaluation of the Mutagenic Potential of High Drop Point Lithium Hydroxystearate Grease (XRR 185A) in the Mouse Lymphoma (L5178Y/TK(sup +/-)) Assay with Cover Letter.
||Mobil Oil Corp., New York.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
||27 Jun 1983
Mutagenic pathways ;
Cell cultures ;
Chemical analysis ;
Lithium hydroxystearate grease ;
||Some EPA libraries have a fiche copy filed under the call number shown.
The Mouse Lymphoma ( L5178Y/TK+/-) Mutagenesis Assay was used to determine the potential of high drop point lithium hydroxystearate grease (XRR 185A) to induce mutations in mammalian cells grown in culture. This assay is a sensitive indicator of the mutagenic potential of compounds from a wide variety of chemical classes. Furthermore, it has the advantage of detecting several classes of carcinogens that are weakly mutagenic or non-mutagenic in the Ames Salmonella/ mammalian microsomal activation assay.