Record Display for the EPA National Library Catalog

RECORD NUMBER: 21 OF 58

Main Title Microarray Technology and Its Applications [electronic resource] /
Type EBOOK
Author Müller, Uwe R.
Other Authors
Author Title of a Work
Nicolau, Dan V.
Publisher Springer Berlin Heidelberg,
Year Published 2005
Call Number R-RZ
ISBN 9783540265788
Subjects Medicine ; Chemistry, Physical organic ; Biomedical engineering ; Nanotechnology
Internet Access
Description Access URL
http://dx.doi.org/10.1007/b137842
Collation XXII, 379 p. 100 illus. Including 16 Color Plates. online resource.
Notes
Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes
General Microarray Technologies -- Array Formats -- Biomolecules and Cells on Surfaces - Fundamental Concepts -- Surfaces and Substrates -- Reagent Jetting Based Deposition Technologies for Array Construction -- Manufacturing of 2-D Arrays by Pin-printing Technologies -- Nanoarrays -- The Use of Microfluidic Techniques in Microarray Applications -- Labels and Detection Methods -- Marker-free Detection on Microarrays -- DNA Microarrays -- Analysis of DNA Sequence Variation in the Microarray Format -- High Sensitivity Expression Profiling -- Applications of Matrix-CGH (Array-CGH) for Genomic Research and Clinical Diagnostics -- Analysis of Gene Regulatory Circuits -- Protein Microarrays -- Protein, Antibody and Small Molecule Microarrays -- Photoaptamer Arrays for Proteomics Applications -- Biological Membrane Microarrays -- Cell & Tissue Microarrays -- Use of Reporter Systems for Reverse Transfection Cell Arrays -- Whole Cell Microarrays -- Tissue Microarrays for Miniaturized High-Throughput Molecular Profiling of Tumors -- Application of Microarray Technologies for Translational Genomics. The genomics revolution would not have been possible without the 'parallelisation' offered by microarray technology. This technological - and commercial - success has been since emulated by other applications areas, with a tremendous amplification of innovation. This book describes the fundamentals and latest developments in microarray technology, as well as its future directions. It presents detailed overviews of the different techniques of fabricating microarrays, of the chemistries and preparative steps involved, of the different types of microarrays, and of the instrumentation and optical issues involved.