Introduction and large scale production of synthetic halogenated organic chemicals over the last 50 years has resulted in a group of contaminants which tend to persist in the environment and resist both biotic and abiotic degradation. The low solubility of these types of contaminants, along with their toxicity and tendency to accumulate in food chains, make them particularly relevant targets for remediation activities. Although the processes involved in dechlorination of many of these organic compounds are well understood in the fields of chemistry and microbiology, technological applications of these processes to environmental remediation are relatively new--particularly at pilot or field scale. It is well established, however, that there are several mechanisms which result in dehalogenation of some classes of organic contaminants, often rendering them less offensive environmentally. These include; stimulation of metabolic sequences through introduction of electron donor and acceptor combinations; addition of nutrients to meet the needs of dehalogenating microorganisms; possible use of engineered micro-organisms; and use of enzyme systems capable of catalyzing reductive dehalogenation.

Cover title. "EPA Project Officer: Judith L. Sims." "Office of Research and Development." "Office of Solid Waste and Emergency Response." "Robert S. Kerr Environmental Research Laboratory." "January 1991" "EPA/540/4-90/054"--Cover. Bibliography: p. 10-12.