Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Alternate enzymes for use in cholinesterase antagonist monitors : CAM's /
Author Goodson, Louis H. ; Appleman, Vicki J.
Other Authors
Author Title of a Work
Appleman, Vicki J.,
CORP Author Midwest Research Inst., Kansas City, MO.;Industrial Environmental Research Lab., Cincinnati, OH.
Publisher Environmental Protection Agency, Office of Research and Development, Industrial Environmental Research Laboratory ; For sale by the National Technical Information Service,
Year Published 1980
Report Number EPA-600/2-80-083; EPA-68-03-0299; MRI-00202
Stock Number PB80-200835
OCLC Number 06576468
ISBN pbk.
Subjects Cholinesterase inhibitors. ; Enzyme inhibitors.
Additional Subjects Enzymes ; Cholinesterase inhibitors ; Monitors ; Organic phosphates ; Carbamates ; Pesticides ; Substitutes ; Chemical agent detection ; Water pollution ; Sampling ; Water pollution detection
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHAM  TD145.E5 EPA-600, 2-80-083 Region 1 Library/Boston,MA 04/29/2016
EJBD ARCHIVE EPA 600-2-80-083 Headquarters Library/Washington,DC 03/21/2011
EJBD  EPA 600-2-80-083 c.1 Headquarters Library/Washington,DC 04/10/2014
EKBD  EPA-600/2-80-083 Research Triangle Park Library/RTP, NC 07/04/2003
ESAD  EPA 600-2-80-083 Region 10 Library/Seattle,WA 03/23/2010
NTIS  PB80-200835 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation x, 72 pages : illustrations ; 28 cm.
The Cholinesterase Antagonist Monitors ('CAM's') normally use cholinesterase as the sensor in the detection of organophosphate and carbamate pesticides. The present investigation has been concerned with a search for alternate enzymes that could be used in the CAM system and that would enable it to detect a variety of other types of environmentally important toxic chemicals including chlorinated hydrocarbons, phenols, aryl phosphates, cyanide, heavy metals, etc. Five enzymes including alkaline phosphatase, carboxyl esterase, glucose oxidase, carbonic anhydrase, and hexokinase have been incubated with dilute solutions of toxic chemicals and the degree of enzyme inhibited by low levels of toxic test compounds. It is concluded that these and similar enzymes are of potential value in the detection and monitoring of toxic substances in water.
Prepared by Midwest Research Institute, under contract no. 68-03-0299. Issued May 1980. Includes bibliographical references.