| Main Title |
Radioimmunoassay of metallothionein / |
| Author |
Friedberg, Felix.
|
| Other Authors |
|
| CORP Author |
Howard Univ., Washington, D.C. Dept. of Biochemistry.;Health Effects Research Lab., Research Triangle Park, N.C. Environmental Toxicology Div. |
| Publisher |
U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory, |
| Year Published |
1978 |
| Report Number |
PB277048; EPA-600/1-78-010; EPA-R-803201 |
| Stock Number |
PB-277 048 |
| OCLC Number |
52465207 |
| Subjects |
Metallothionein ;
Radioimmunoassay
|
| Additional Subjects |
Proteins ;
Amino acids ;
Metals ;
Cadmium ;
Zinc ;
Copper ;
Transport properties ;
Chemical composition ;
Assaying ;
Radioimmunoassay ;
Metallothionein proteins
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EJBD |
EPA 600-1-78-010 |
c.1 |
Headquarters Library/Washington,DC |
06/09/2014 |
| EKBD |
EPA-600/1-78-010 |
|
Research Triangle Park Library/RTP, NC |
06/27/2003 |
| ELBD ARCHIVE |
EPA 600-1-78-010 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
| ELBD RPS |
EPA 600-1-78-010 |
repository copy |
AWBERC Library/Cincinnati,OH |
07/07/2016 |
| NTIS |
PB-277 048 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
iii, 12 pages ; 28 cm. |
| Abstract |
The goal of this project was to develop a radioimmunoassay for metallothionein. Since this protein is involved with the transport of cadmium in biological systems and may in fact protect against cadmium poisoning, the ability to monitor the levels in the human population is of the utmost importance to evaluation of the hazards of environmental cadmium exposure. While researchers do not agree whether copper thioneins and zinc thioneins of rats are identical, this study found in preliminary analysis that zinc thionein appears to have a composition similar to that of copper chelatins. It is recommended that development of a radioimmunoassay should not be attempted until the putative metallothioneing is clearly characterized. There are too many kinds of metallothionein induced by the injection of different metals according to the reports in the literature. They must be properly identified first. |
| Notes |
Project Officer: Larry L. Hall. "January 1978." "EPA-600/1-78-010." PB 277 048--NTIS. Includes bibliographical references. |
