Record Display for the EPA National Library Catalog

RECORD NUMBER: 41 OF 107

Main Title Induction and Reduction of Sister Chromatid Exchange by CCNU in Human Lymphocytes in Vitro.
Author McKenzie, W. H. ; Lambert, B. ;
CORP Author North Carolina State Univ. at Raleigh.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1983
Report Number EPA-R-805739; EPA-600/J-83-053;
Stock Number PB84-101666
Additional Subjects Lymphocytes ; Chromatids ; Cesium 137 ; In vitro analysis ; Humans ; Dosage ; Chromosomes ; Reprints ; Sister chromatid exchange
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NTIS  PB84-101666 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 13p
Abstract
The chromosome aberration yield for human lymphocytes exposed in vitro to various doses of 137 Cesium has been studied. Dicentric, total acentric and excess acentric data were seen to follow a Possion distribution. Calculated total hits demonstrated over-dispersion which could possibly be accounted for by a greater occurrence of single-hit phenomena being repaired than two-hit exchange processes. The resulting distribution generally contained an under-representation of cells with odd numbers of hits and an over-representation of zero- and even-hit classes as compared with Poisson predicted values.