Record Display for the EPA National Library Catalog
RECORD NUMBER: 709 OF 727| Main Title | Validation of an In Vitro Bioaccessibility Test Method for Estimation of Bioavailability of Arsenic from Soil and Sediment. | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Author | S. Griffin ; Y. Lowney | |||||||||||
| CORP Author | Environmental Protection Agency, Denver, CO. Region VIII. | |||||||||||
| Year Published | 2012 | |||||||||||
| Report Number | Proj. ER-200916 | |||||||||||
| Stock Number | ADA579125 | |||||||||||
| Additional Subjects | Arsenic ; In vitro analysis ; Sediments ; Soils ; Test methods ; Estcp collection ; Estcp(Environmental security technology certification program) ; In vitro bioaccessibility ; Relative bioavailability | |||||||||||
| Holdings |
|
|||||||||||
| Collation | 277p | |||||||||||
| Abstract | A method is described for measuring the in vitro bioaccessibility (IVBA) of arsenic in soil or soil-like media, and using the measured IVBA value to estimate the relative bioavailability (RBA) in swine or monkeys using empiric regression models developed from 20 (swine) or 17 (monkey) calibration soils. The correlation coefficients for the models are high (0.85 for swine, 0.87 for monkey), and the precision of the method is high, both within and between laboratories. This method is the most thoroughly tested, calibrated, and validated IVBA approach for estimation of arsenic RBA that has been described to date. |