Record Display for the EPA National Library Catalog

RECORD NUMBER: 22 OF 37

Main Title Life-Cycle Mutants of Chinese Hamster Ovary Cells, October 1--November 30, 1976.
Author Barnhart, B. J. ; Cox, S. H. ; Okinaka., R. T. ;
CORP Author Los Alamos Scientific Lab., N.Mex.;Energy Research and Development Administration.
Year Published 1976
Report Number W-7405-ENG-36 ;EPA-IAG-D5-E6;
Stock Number LA-6604-PR
Additional Subjects Animal cells ; Hydrocarbons ; Mutagens ; Mutations ; Bioassay ; Biological effects ; Biological radiation effects ; Cell cultures ; Genetics ; Hamsters ; Ionizing radiations ; Life cycle ; Mutagenesis ; Mutants ; Radioinduction ; Tissue cultures ; ERDA/560305 ; ERDA/560121 ; ERDA/550400
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Status
NTIS  LA-6604-PR Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 4p
Abstract
A t/sub s/ growth mutant of the cell line DON CCL is being characterized for reversion frequencies following exposure to chemical mutagens and ionizing radiation. The mutagen concentrations and mutation expression times are being defined for optimal reversion frequencies. The Ames Salmonella/mammalian liver microsome test system has been set up and will be used as an ancillary assay for mutagenicity for various polycyclic hydrocarbons prior to assessing these compounds in the tissue culture assay system. (ERA citation 02:027575)