| Main Title |
Cardiovascular Effects of o,p'-DDD. |
| Author |
Cueto, Jr., Cipriano ;
|
| CORP Author |
Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab. |
| Year Published |
1970 |
| Stock Number |
PB-277 613 |
| Additional Subjects |
Pesticides ;
Epinephrine ;
Norepinephrine ;
Insecticides ;
Cardiovascular system ;
Toxicology ;
Dogs ;
Laboratory animals ;
Experimental data ;
Dosage ;
Responses ;
Histamines ;
Blood pressure ;
Blood plasma ;
Histology ;
Bioassay ;
Reprints ;
DDD insecticide ;
Glucocorticoids ;
Toxic substances
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-277 613 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
2p |
| Abstract |
Daily oral administation of o,p'-DDD to dogs produced glucocorticoid deficiency. Blood pressure and heart contractile force and rate response to graded doses of epinephrine and norepinephrine were determined in treated and untreated dogs. Vasopressor and cardioaccelerator responses to ouabain were similar in treated and untreated dogs. The induced glucocorticoid deficiency produced little apparent direct circulatory effect but diminished the ability to withstand stressful procedures such as thoracotomy and multiple injections of vasopressor amines. |
