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RECORD NUMBER: 11 OF 23

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Main Title

Interim Report of Mouse Skin-Painting Test Results with Aromatic Petroleum Pitch with Cover Letter dated 07/14/80.

CORP Author

Standard Oil Co. (Ohio), Cleveland.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.

Publisher

21 Jul 1980

Year Published

1980

Report Number

8HEQ-0780-0353;

Stock Number

OTS-0204860

Additional Subjects

Skin diseases ; Mice ; Toxicity ; Solvents ; Dosage ; Carcinoma ; Tumors ; Aromatics ; Body fluids ; Toluene ; Laboratory tests ; Exposure ; Bioavailability ; Laboratory animals ; Aromatic petroleum pitch ; Standard Oil Company

Holdings

Library	Call Number	Additional Info	Location	Last Modified	Checkout Status
NTIS	OTS-0204860	Some EPA libraries have a fiche copy filed under the call number shown.		07/26/2022

Collation

50p

Abstract

This report summarizes significant data obtained after 59 weeks of a projected lifetime mouse skin-painting study instituted to assay the carcinogenic potential of products produced from the oxidative condensation of an intermediate clarified oil solvent extract (CAS Registry No. 64741-62-4). The results obtained support the conclusion that at high dose levels when all or a portion of the test materials are made bioavailable via salvation in toluene, skin tumors are induced. The bioavailability of the solid test materials via solvation in normal body fluids (e.g. sweat, saliva, gastro-intestinal fluids, etc.) was not addressed in this study.

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