Record Display for the EPA National Library Catalog


Main Title Interim Report of Mouse Skin-Painting Test Results with Aromatic Petroleum Pitch with Cover Letter dated 07/14/80.
CORP Author Standard Oil Co. (Ohio), Cleveland.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 21 Jul 1980
Year Published 1980
Report Number 8HEQ-0780-0353;
Stock Number OTS-0204860
Additional Subjects Skin diseases ; Mice ; Toxicity ; Solvents ; Dosage ; Carcinoma ; Tumors ; Aromatics ; Body fluids ; Toluene ; Laboratory tests ; Exposure ; Bioavailability ; Laboratory animals ; Aromatic petroleum pitch ; Standard Oil Company
Library Call Number Additional Info Location Last
NTIS  OTS-0204860 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 50p
This report summarizes significant data obtained after 59 weeks of a projected lifetime mouse skin-painting study instituted to assay the carcinogenic potential of products produced from the oxidative condensation of an intermediate clarified oil solvent extract (CAS Registry No. 64741-62-4). The results obtained support the conclusion that at high dose levels when all or a portion of the test materials are made bioavailable via salvation in toluene, skin tumors are induced. The bioavailability of the solid test materials via solvation in normal body fluids (e.g. sweat, saliva, gastro-intestinal fluids, etc.) was not addressed in this study.