Record Display for the EPA National Library Catalog
RECORD NUMBER: 33 OF 103| Main Title | Evaluation of the potential carcinogenicity of chlornaphazine (494-03-1) / | |||||||||||
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| CORP Author | Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. | |||||||||||
| Publisher | U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ; | |||||||||||
| Year Published | 1988 | |||||||||||
| Report Number | EPA/600/8-91/089; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-053 | |||||||||||
| Stock Number | PB93-185239 | |||||||||||
| Subjects | Aromatic compounds--Carcinogenicity ; Chlornapazine--Carcinogenicity | |||||||||||
| Additional Subjects | Carcinogens ; Toxicity ; Risk assessment ; Humans ; Animals ; Dose-response relationships ; Carcinogenicity tests ; Chlornaphazine ; CAS 494-03-1 | |||||||||||
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| Collation | 15 pages ; 28 cm | |||||||||||
| Abstract | Chlornaphazine is a possible human carcinogen, classified as weight-of-evidence Group C under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). Evidence on potential carcinogenicity from animal studies is Limited, and the evidence from human studies is Inadequate. Data available are inadequate for calculating a potency factor (F) and no quantitative inferences can be made according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Chlornaphazine is, therefore, assigned to the median potency factor range and placed in potency group 2. Combining the weight-of-evidence group and the potency group, chlornaphazine is assigned a LOW hazard ranking for the purposes of RQ adjustment. |
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| Notes | Cover title. "June 1988." Includes bibliographical references. Microfiche. |