Record Display for the EPA National Library Catalog
RECORD NUMBER: 280 OF 335| Main Title | NTP technical report on the toxicology and carcinogenesis studies of [alpha]-methylstyrene (CAS no. 98-83-9) in F344/N rats and B6C3F1 mice (inhalation studies) / | |||||||||||
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| Publisher | National Toxicology Program, National Institutes of Health, Public Health Service, U.S. Department of Health and Human Services, | |||||||||||
| Year Published | 2006 | |||||||||||
| OCLC Number | 241649401 | |||||||||||
| Subjects | Carcinogenicity testing ; Toxicity testing ; Carcinogenicity Tests | |||||||||||
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| Collation | 210 pages, 4 unnumbered pages of plates : illustrations ; 28 cm | |||||||||||
| Notes | "November 2007." Includes bibliographical references. |
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| Contents Notes | Explanation of levels of evidence of carcinogenic activity -- Technical reports review subcommittee -- Summary of technical reports review subcommittee comments -- Introduction -- Materials and methods -- Results -- Discussion and conclusion -- References -- Appendices. Summary of lesions in male rats in the 2-year inhalation study of [alpha]-methylstyrene -- Summary of lesions in female rats in the 2-year inhalation study of [alpha]-methylstyrene -- Summary of lesions in male mice in the 2-year inhalation study of [alpha]-methylstyrene -- Summary of lesions in female mice in the 2-year inhalation study of [alpha]-methylstyrene -- Genetic toxicology -- Clinical pathology results -- Organ weights and organ-weight-to-body-weight ratios -- Reproductive tissue evaluations and estrous cycle characterization -- Chemical characterization and generation of chamber concentrations -- Ingredients, nutrient composition, and contaminant levels in NIH-2000 rat and mouse ration -- Sentinel animal program -- Physiologically based pharmokinetic model -- Metabolism and chemical disposition of [alpha]-methylstyrene. |