Record Display for the EPA National Library Catalog

RECORD NUMBER: 30 OF 31

Main Title Theoretical foundations of cancer chemotherapy introduced by computer models
Author Jackson, Robert C.
Publisher Academic Press,
Year Published 1992
OCLC Number 25592026
ISBN 0123790301
Subjects Cancer--Chemotherapy--Computer simulation ; Pharmacokinetics--Computer simulation ; Cancer cells--Computer simulation ; Antineoplastic Agents--pharmacokinetics ; Computer Simulation ; Models, Chemical ; Neoplasms--drug therapy
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJBM  RC271.C5J33 1992 Headquarters Library/Washington,DC 11/21/1997
Collation xiv, 447 p. : ill. ; 24 cm. + 1 computer disk (5 1/4 in.)
Notes
System requirements for computer disk: IBM PC or compatible; IBM-BASIC, BASICA, or Microsoft GWBASIC (need Microsoft Quick Basic 4.5 to compile source codes). Includes bibliographical references (p. 427-435) and index.
Contents Notes
Introduction: models as tools for teaching and research -- Cell cycle effects of drugs -- Anticancer drug selectivity -- Quiescent cells, differentiated cells, and lost cells -- Pharmacokinetic models -- Invasion and metastasis -- Blood-brain barrier -- Cancer treatment and the immune response -- Drug resistance and its implications for treatment strategy -- Growth kinetics of large tumors -- Biochemical basis of anticancer drug selectivity -- Biochemical principles of drug interaction -- Cytokinetics, pharmacokinetics, and inhibition kinetics: a unified model.