Record Display for the EPA National Library CatalogRECORD NUMBER: 5 OF 14
|Main Title||Evaluation of the Ototoxic Potential of Cumene Inhalation Exposure in F344 Rats with Cover Letter.|
|CORP Author||Dow Chemical Co., Midland, MI.; Chemical Manufacturers Association, Washington, DC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.|
|Additional Subjects||Toxicology ; Health effects ; Cumene (98-82-8) ; Neurotoxicity ; Mammals ; Rats ; Inhalation ; Toxic substances ; Laboratory animals ; CAS No 98-82-8|
Cumene (CAS No. 98-82-8) was evaluated for neurotoxicity in a functional test of auditory brainstem responses to tone pips. The test substance was administered by inhalation to rats (10/sex/group) at 0, 50, 100, 500, and 1,200 ppm 6 hours/day, 5 days/week for 13 weeks. There were no effects on the auditory function of rats after exposure to cumene.