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Main Title Oral Toxicity in Rats Test Results with Cover Letter Dated 12/17/1982.
CORP Author Mb Research Laboratories, Inc.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1982
Report Number 40-8258074
Stock Number OTS0514286
Additional Subjects Toxicology ; Health effects ; 1 ; 2 ; 4-trimethylbenzene ; Acute Toxicity ; Mammals ; Rats ; Oral ; Gavage ; Toxic substances ; Laboratory animals ; CAS No 95-63-6
Library Call Number Additional Info Location Last
NTIS  OTS0514286 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 6p
Acute oral toxicity was evaluated in groups of 10 male Wistar rats administered single doses of 98% pseudocumene by oral gavage at levels of 3.51, 5.0, 7.12 and 10.14 g/kg of body weight. Mortality was observed in 3 animals in the 5.0 g/kg dose group, 7 in the 7.12 g/kg dose group, and all 10 in the highest dose group. The LD50 value was calculated to be 6.0 g/kg of body weight, with confidence limits of 4.92 - 7.32 g/kg, by the Litchfield and Wilcoxon method. Clinical observations included lethargy, ptosis, ataxia, and piloerection. Gross necropsy findings were not reported.