Record Display for the EPA National Library CatalogRECORD NUMBER: 1 OF 5
|Main Title||Frigen 113 Test for Mutagenicity in Bacteria Strains in the Absence and Presence of a Liver Preparation with Cover Letter Dated 07/21/1989.|
|CORP Author||Hoechst Celanese Corp., Summit, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.|
|Additional Subjects||Toxicology ; Health effects ; 1 ; 1 ; 2-trichloro- 1 ; 2 ; 2-trifluoroethane (76-13-1) ; Genotoxicity ; Gene Mutations ; Bacteria ; In Vitro ; Toxic substances ; Laboratory animals ; CAS No 76-13-1|
The mutagenicity of Frigen 113 (1,1,2-trichloro- 1,2,2-trifluoroethane) was evaluated in Salmonella tester strains TA98, TA100, TA1537, and TA1538 (Ames Test), both in the presence and absence of added metabolic activation by Aroclor-induced rat liver S9 fraction. The material was tested for mutagenicity at a concentration of 10% (v/v) using the dessicator method. Frigen 113 did not cause a reproducible positive response in any of the bacterial tester strains, either in the presence or absence of added metabolic activation.