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Main Title Frigen 113 Test for Mutagenicity in Bacteria Strains in the Absence and Presence of a Liver Preparation with Cover Letter Dated 07/21/1989.
CORP Author Hoechst Celanese Corp., Summit, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1989
Report Number 86-890001292
Stock Number OTS0520796
Additional Subjects Toxicology ; Health effects ; 1 ; 1 ; 2-trichloro- 1 ; 2 ; 2-trifluoroethane (76-13-1) ; Genotoxicity ; Gene Mutations ; Bacteria ; In Vitro ; Toxic substances ; Laboratory animals ; CAS No 76-13-1
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  OTS0520796 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 9p
Abstract
The mutagenicity of Frigen 113 (1,1,2-trichloro- 1,2,2-trifluoroethane) was evaluated in Salmonella tester strains TA98, TA100, TA1537, and TA1538 (Ames Test), both in the presence and absence of added metabolic activation by Aroclor-induced rat liver S9 fraction. The material was tested for mutagenicity at a concentration of 10% (v/v) using the dessicator method. Frigen 113 did not cause a reproducible positive response in any of the bacterial tester strains, either in the presence or absence of added metabolic activation.