Record Display for the EPA National Library CatalogRECORD NUMBER: 7 OF 10
|Main Title||Initial Submission: Letter from Rhone-Poulenc, Inc. to USEPA regarding Teratology Screen Sgtudies of Various Compounds in Rats with Attachments and Cover Letter dated 10/27/1992.|
|CORP Author||Rhone-Poulenc Ag Co., Research Triangle Park, NC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.|
|Additional Subjects||Toxicology ; Health effects ; Various compounds ; Reproduction ; Fertility effects ; Teratogenicity ; Mammals ; Rats ; Oral ; Gavage ; CAS No 75-07-0 ; CAS No 109-52-4 ; CAS No 111-14-8 ; CAS No 112-05-0 ; CAS No 1680-21-3 ; CAS No 3290-92-4 ; CAS No 13048-33-4 ; CAS No 15625-89-5 ; CAS No 29590-42-9 ; CAS No 42978-66-5|
The purpose of this study was to evaluate the embryo/fetal toxicity and teratogenic effects of a series of eleven compounds (C-180, C-181, C-182, C-236, C-253, C-254, C-255, C-256, C-257, C-258, and C-259) when administered by oral gavage to pregnant rats from Days 6 through 15 of gestation. Breeding began on May 11, 1982, and cesarean sections were completed on June 24, 1982. This report presents and discusses the methods and results from the study.