||Initial Submission: Mutagenicity Evaluation of 1,6-Hexanediol Diacrylate in the Mouse Lymphoma Forward Mutation Assay with Cover Letter dated 09/04/1992.
||Litton Bionetics, Inc., Bethesda, MD.; Rhone-Poulenc Ag Co., Research Triangle Park, NC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
Toxic substances ;
6 hexanediol diacrylate ;
Gene mutation ;
In vitro ;
CAS No 13048-33-4
||Some EPA libraries have a fiche copy filed under the call number shown.
This study is being reported under Section 8(e) CAP because acrylates generally produce positive results in the mouse lymphoma assay. In this study, the test material induced an increase in the mutant frequency at the TK Locus in L5178Y mouse lymphoma cells at concentrations of 0.0094 and 0.0125 pl/ml without activation. No increase in mutant frequency was observed with activation.