| Main Title |
Toxicity Studies on Dimethylformamide (DMF) and Dimethylacetamide (DMAC), with Cover Letter dated 09/29/1995 (Sanizited). |
| CORP Author |
Du Pont de Nemours (E.I.) and Co., Wilmington, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1995 |
| Report Number |
OTS-86960000179S |
| Stock Number |
OTS0558319 |
| Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
Laboratory animals ;
Subchronic toxicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Rabbits ;
Dermal ;
Primary eye irritation ;
Inhalation ;
CAS No 68-12-2 ;
CAS No 127-19-5
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0558319 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
9p |
| Abstract |
In order to obtain comparative toxicity data on dimethylfornamide and dimethylacetamide for the Sales Division of the Industrial and Biochemicals Department, the following experiments were conducted on each compound: (1) Subacute oral toxicity tests with six rats each receivink nine doses of 450 ag/kg/day over a two-week period. (2) Subacute skin absorption tests with six rabbits each receiving nine daily doses of 2000 mg/kg over a two-veek period. (3) Subacute inhalation tests in which rats were exposed six hours daily for a maximum of 5 exposures to 2500 ppm of DHP, and 10 exposures to 2100 ppm of DMAC. (4) Acute eye irritation tests with rabbits. |
