| Main Title |
Initial Submission: Acute Oral and Dermal Toxicity of B-Aminocrotonitrile in Rats, Mice, and Guinea Pigs with Cover Letter dated 09/08/1992. |
| CORP Author |
Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
8EHQ-0992-10989 |
| Stock Number |
OTS0571027 |
| Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
B-aminocrotonitrile ;
Acute toxicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Parenteral ;
Intraperitoneal ;
Mice ;
Guinea pigs ;
Dermal ;
CAS No 1118-61-2
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0571027 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
5p |
| Abstract |
The report pertains to 3-amino-2-butenenitrile (synonym: beta-aminoctotonitrile) (CAS No. 1118-61-2) and is being submitted because of lethality with central nervous system signs observed in an acute oral toxicity test in rats and mice. The oral LDa is 50 mg/kg in rats and 50-100 mg/kg in mice. The material is also a strong skin irritant and its dermal LDa is 0.5-1.0 g/kg in guinea pigs. The report is being identified as a study involving other than human effects (Unit II.B.2.b of CAP Agreement). |
